How is osteomyelitis generally caused?

Osteomyelitis is primarily caused by infection, and one common route for this infection is through the bloodstream. When bacteria or other pathogens enter the bloodstream, they can travel to the bones, particularly if the individual has predisposing factors such as an existing infection, weakened immune system, or chronic health conditions. This hematogenous spread leads to inflammation and infection of the bone tissue, resulting in osteomyelitis. Understanding the systemic nature of infections and their potential to spread to skeletal structures is crucial in recognizing the underlying mechanisms of this condition. Other factors such as direct injury to the bone can also contribute to osteomyelitis in some cases, especially if they allow infectious agents direct access to the bone, but the primary mechanism for many cases is through the bloodstream.